Like all good stories, ours began when Dr. Govind Rao pursued his fascination to connect the environment of the cell with its metabolic behavior — and share his research with experts and practitioners in the biotech industry.
Whenever Dr. Rao gave a seminar to industry audiences, he would hear the woes of bioprocessing engineers. They would share their respective challenges in trying to effectively use conventional pH and oxygen electrodes in experiments. Clark electrodes for dissolved oxygen were bulky and expensive. They were also subject to drift. And not sensitive enough at physiological ranges. pH electrodes on the other hand were no better. Electrodes were too big and not practical for use in T-flasks or shake flasks where most process development begins. The issues were real, and rampant.
In 2011, Scientific Industries (SI) – creator of the ubiquitous Vortex-Genie® – acquired Fluorometrix and changed the company name to Scientific Bioprocessing Inc. (SBI). It was the vision of SI’s Chairman, Mr. Joe Cremonese, to combine SI’s expertise in creating optimal cell growth environments with the SBI optical sensor technology to make the lives of cell scientists and bioprocess engineers easier and more productive with a faster trajectory to critical research results.
The fact that, in 2019, the Nobel Prize for Physiology and Medicine was awarded for the discovery of how cells sense oxygen levels is testament to Dr. Rao and his team’s prescience on the importance of this paradigm shift.
But even today, years after Dr. Rao started his journey of discovery, few researchers are aware of non-invasive tools that allow real-time oxygen and pH measurements in cell cultures.
Today, SBI is a collective of scientists, engineers and business people committed to making intelligent, dynamic process scouting devices with dissolved oxygen and pH sensors easily accessible and available to the thousands of cell scientists and bioprocessing engineers who are on the cutting edge of scientific and medical breakthroughs. Our job is to power your scientific audacity. For every experiment, every day.