DOTS is coming to Cell Culture! January 2025 - Subscribe to our Newsletter for Updates

Simplify your Bioprocessing.

Make informed decisions by accessing critical process parameters in shake flasks.

Explore The DOTS Platform

The DOTS Platform

Build a Smarter Shake Flask, One Parameter at a Time

Untitled design (10)
Sensing & Controlling

Sensing & Controlling

Monitor critical process parameters like DO and biomass and add fed-batch capabilities to your shake flask.

Data Transfer

Data Transfer

Data is transferred from our shake flask sensors to the DOTS Software via wired connection.

Sensor Handling & Data Monitoring

Sensor Handling & Data Monitoring

Use our cutting edge DOTS Software to gain access to actionable insights and control of your shake flask bioprocesses.

Sensors to Fit Your Vessel Type

 

For Shake Flasks

For Bioreactors

Explore Our Applications

Biomass Monitoring

Learn More

Biomass-Based Feeding

Learn More

Dissolved Oxygen (DO) Monitoring

Learn More

Microbial Screening

Learn More
Biomass Monitoring

Biomass Monitoring

Biomass monitoring follows the development of cell concentration over time and characterizes the growth of the cultivated microorganism. Most microbial growth curves can be broken down into six distinctive growth phases.

Learn More
Biomass-based feeding

Biomass-Based Feeding In Shake Flasks

Automated biomass-based feeding allows an initiation of liquid injection that is dependent on cell growth and more fine-tuned to the needs of your cultivation.

Learn More
Dissolved Oxygen monitoring

Dissolved Oxygen (DO) Monitoring

Oxygen is often considered a limiting factor in bioprocessing because if it falls below certain thresholds it can result in slowed metabolism, altered product formation, changed growth behavior, and in worst case, cell death.

Learn More
Microbial Fermentation

Microbial Screening In Shake Flasks

Improved scalability and cost-effectiveness make shake flasks an ideal choice for researchers conducting microbial screening assays.

Learn More

Lets chat!

Interested in one of our products or have questions about your bioprocessing?

SPEAK TO AN EXPERT

Trusted by Industry and Academia Across the Globe

Fed-batch In Shake Flasks Increases Protein Yields

clariant protein fed-batch

"By using the LIS, I can now continuously feed glucose in shake flasks. This improves the transferability of results from shake flask experiments to bioreactor runs."

Dr. Kambiz Morabbi Heravi (Project Manager Strain Engineering, Clariant)

Growth Rate Monitoring Reveals Best Media Composition

bond-media-optimization

"The real power of the CGQ is being able to sample at specific points of interest based on the continuous, high-resolution data. Otherwise, with manual sampling, it is just a shot in the dark. You never really know where in the growth curve the organism is."

- Raul Reveles (Bond Pet Foods)

CGQ BioR's Online Biomass Monitoring Aligns Well With Offline Data

SBI-Success-Table-3-1 (1)

"The CGQ BioR system provides precise growth curves with a very dense sampling interval, freeing my team for tasks with higher added value."

- Dipl. Ing. Andreas Hoffman (Technical University Dresden)

Stable Biomass Data Even Under Extreme Conditions

Kopie von Centrale Supélec Image (7) (1)

"The CGQ BioR is well suited for monitoring biomass of cultivations with thermophilic organisms that require high temperatures and long fermentation times."

- Dipl. Ing. Robert Klausser (IBD Group, TU Wien)

clariant-logo-grey-1
bond-logo-grey
logo-tud-gray
logo-tuw-gray

Headline introducing the Process.

Lorem ipsum dolor sit amet, consectetur
adipiscing elit et am iatum.

Actionable benefit

This is a concise supporting benefit statement explaining how awesome the software is

Actionable benefit

This is a concise supporting benefit statement explaining how awesome the software is

Actionable benefit

This is a concise supporting benefit statement explaining how awesome the software is

list-icon-blue list-icon-2
list-icon-blue list-icon-2
list-icon-blue list-icon-2

Discover the Latest Resources from sbi

sbi broadcast

Broadcast

Join us as we interview experts from the field. Listen Now →
sbi Newsletter (2)

Newsletter

Stay up to date with sbi news and happenings. Subscribe Now→
sbi blog

Blog

Our latest articles on trends and tips in bioprocessing. Read Now →